Maman Lab | Maman Lab

Welcome to Maman's lab

Genomic instability & Cancer

The necessary evil of genome instability

Genome instability is a hallmark of cancer. Our lab combines sensitive, high-throughput, genomic assays, and computational modeling, in order to crack the genomic code that drives genome instability in different cell-types, pathologies and conditions, and to grasp the landscape of DNA lesions in cancer.

Recent Publications

Hanout-Chuiko, Wessal ; Pachakar, Sunil ; Foqara, Rawan et al. / The nonamer code for RAG-mediated recombination in vivo. ב-: Nucleic Acids Research. 2025 ; כרך 53, מס' 22.

למידע נוסף

Sibony-Benyamini, Hadas ; Jbara, Rose ; Shubash Napso, Tania et al. / The landscape of Helicobacter pylori-mediated DNA breaks links bacterial genotoxicity to its oncogenic potential. ב-: Genome Medicine. 2025 ; כרך 17, מס' 1.

למידע נוסף

Perez, Shira ; Lavi-Itzkovitz, Anat ; Gidoni, Moriah et al. / High-Resolution Genomic Profiling of Liver Cancer Links Etiology With Mutation and Epigenetic Signatures. ב-: CMGH. 2023 ; כרך 16, מס' 1. עמודים 63-81.

למידע נוסף

Tarsalainen, Alina ; Maman, Yaakov ; Meng, Fei Long et al. / Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences. ב-: Journal of Immunology. 2022 ; כרך 208, מס' 1. עמודים 143-154.

למידע נוסף

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