The Drug Development Lab
Our research group takes a multidisciplinary approach to developing new drug candidates, combining pharmacology, molecular biology, biochemistry, molecular modeling, and nanotechnology. We begin by identifying a key target protein involved in a disease, using its 3D structure to design potential small molecules through computer modeling. These molecules are synthesized, tested in vitro, and evaluated for therapeutic effects in animal models—all conducted in our lab.
We strive to combat devastating diseases, driven by the belief that medicinal chemistry can improve human health and well-being.
Fields of interest
Novel Alkylating Agent for Effective Glioblastoma Therapy
Development of the leukocyte transendothelial migration inhibitors
Development of novel Nrf-2 activators (Nrf-2/KEAP1 interaction blockers)
Development of bioactive peptides and peptide based research tools.
Human α1-antitrypsin based therapeutic peptides as a novel wound healing treatment.
Development of novel chemical chaperones as drug candidates against misfolded proteins related diseases.
Green recycling of wastewaters through cutting-edge microalgae and plant cultivation systems in extreme environments.
Recent Publications
Unified Synthesis of Electron-Deficient 1,4- and 1,1,4-Substituted 1,3-Dienes through a Base-Promoted Allylation Followed by Retro-Michael Vinylogous Dehydrosulfinylation
Intracellular spatially-targeted chemical chaperones increase native state stability of mutant SOD1 barrel
A novel facial cream based on skin penetrable Hemp oil microparticles
Moderately lipophilic 2-(Het)aryl-6-dithioacetals, 2-phenyl-1,4-benzodioxane-6-dithioacetals and 2-phenylbenzofuran-5-dithioacetals: Synthesis and primary evaluation as potential antidiabetic AMPK-activators.
Video Competition Lab
Video Competition Lab
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