With the growth in cancer incidence, the market continuously demands development of new and novel biomarkers for early cancer diagnosis and chemotherapy targets. Hypoxia is a feature of all solid tumors. It is associated with low oxygen level, which makes it a high priority target for cancer therapy. In our lab, we are integrating the knowledge gained in the group on the Cu(I) transfer mechanism and the redox properties of copper, to develop new biomarkers for imaging of hypoxic cells.

Shenberger, Y.; Ruthstein, S.; Copper-containing complex and uses thereof. USA Provisional patent application. 2017, 62/583, 630. PCT IL2018/051211 (9/11/18). IL 274525; US 16/868,618 (07/05/20)