My Publications
2025
Zheng, X, Chiou, CY, Ekim, SD, Kouznetsova, TB, Vakil, J, Hu, Y, Sapir, L, Chen, D, Wang, Z, Rubinstein, M, Gong, JP, Sottos, NR & Craig, SL 2025, 'Tuning the Ultimate Strain of Single and Double Network Gels Through Reactive Strand Extension', ACS Central Science, vol. 11, no. 10, pp. 1882-1891. https://doi.org/10.1021/acscentsci.5c00932
Igbaria-Jaber, Y, Mandato, A, Hofmann, L, Shenberger, Y, Gevorkyan-Airapetov, L, Sapir, L, Saxena, S & Ruthstein, S 2025, 'Tracking Copper sensing operon Repressor (CsoR) oligomerization in solution using Electron Paramagnetic Resonance spectroscopy', Protein Science, vol. 34, no. 10, e70303. https://doi.org/10.1002/pro.70303
2024
Peri, L, Matzov, D, Huxley, DR, Rainish, A, Fierro, F, Sapir, L, Pfeiffer, T, Waterloo, L, Hübner, H, Peleg, Y, Gmeiner, P, McCormick, PJ, Weikert, D, Niv, MY & Shalev-Benami, M 2024, 'A bitter anti-inflammatory drug binds at two distinct sites of a human bitter taste GPCR', Nature Communications, vol. 15, no. 1, 9991. https://doi.org/10.1038/s41467-024-54157-6
2023
Chen, D, Panyukov, S, Sapir, L & Rubinstein, M 2023, 'Elasticity of Slide-Ring Gels', ACS Macro Letters, vol. 12, no. 3, pp. 362-368. https://doi.org/10.1021/acsmacrolett.3c00010
Wang, S, Hu, Y, Kouznetsova, TB, Sapir, L, Chen, D, Herzog-Arbeitman, A, Johnson, JA, Rubinstein, M & Craig, SL 2023, 'Facile mechanochemical cycloreversion of polymer cross-linkers enhances tear resistance', Science, vol. 380, no. 6651, pp. 1248-1252. https://doi.org/10.1126/science.adg3229
Sapir, L, Brock, J, Chen, D, Liao, Q, Panyukov, S & Rubinstein, M 2023, 'How a Chain Can Be Extended While Its Bonds Are Compressed', ACS Macro Letters, vol. 12, no. 7, pp. 894-900. https://doi.org/10.1021/acsmacrolett.3c00097
2022
Speer, SL, Stewart, CJ, Sapir, L, Harries, D & Pielak, GJ 2022, 'Macromolecular Crowding Is More than Hard-Core Repulsions', Annual Review of Biophysics, vol. 51, pp. 267-300. https://doi.org/10.1146/annurev-biophys-091321-071829
2021
Danielsen, SPO, Beech, HK, Wang, S, El-Zaatari, BM, Wang, X, Sapir, L, Ouchi, T, Wang, Z, Johnson, PN, Hu, Y, Lundberg, DJ, Stoychev, G, Craig, SL, Johnson, JA, Kalow, JA, Olsen, BD & Rubinstein, M 2021, 'Molecular Characterization of Polymer Networks', Chemical Reviews, vol. 121, no. 8, pp. 5042-5092. https://doi.org/10.1021/acs.chemrev.0c01304
Olgenblum, GI, Wien, F, Sapir, L & Harries, D 2021, 'β-Hairpin Miniprotein Stabilization in Trehalose Glass Is Facilitated by an Emergent Compact Non-Native State', Journal of Physical Chemistry Letters, vol. 12, pp. 7659-7664. https://doi.org/10.1021/acs.jpclett.1c02379
2020
Olgenblum, GI, Sapir, L & Harries, D 2020, 'Properties of Aqueous Trehalose Mixtures: Glass Transition and Hydrogen Bonding', Journal of Chemical Theory and Computation, vol. 16, no. 2, pp. 1249-1262. https://doi.org/10.1021/acs.jctc.9b01071
Sapir, L & Harries, D 2020, 'Restructuring a Deep Eutectic Solvent by Water: The Nanostructure of Hydrated Choline Chloride/Urea', Journal of Chemical Theory and Computation, vol. 16, no. 5, pp. 3335-3342. https://doi.org/10.1021/acs.jctc.0c00120
2019
Viner, H, Nitsan, I, Sapir, L, Drori, S & Tzlil, S 2019, 'Mechanical Communication Acts as a Noise Filter', iScience, vol. 14, pp. 58-68. https://doi.org/10.1016/j.isci.2019.02.030
Hassan, A, Sapir, L, Nitsan, I, Greenblatt Ben-El, RT, Halachmi, N, Salzberg, A & Tzlil, S 2019, 'A Change in ECM Composition Affects Sensory Organ Mechanics and Function', Cell Reports, vol. 27, no. 8, pp. 2272-2280.e4. https://doi.org/10.1016/j.celrep.2019.04.092
2017
Sapir, L & Harries, D 2017, 'Revisiting Hydrogen Bond Thermodynamics in Molecular Simulations', Journal of Chemical Theory and Computation, vol. 13, no. 6, pp. 2851-2857. https://doi.org/10.1021/acs.jctc.7b00238
Sapir, L & Tzlil, S 2017, 'Talking over the extracellular matrix: How do cells communicate mechanically?', Seminars in Cell and Developmental Biology, vol. 71, pp. 99-105. https://doi.org/10.1016/j.semcdb.2017.06.010
2016
Sapir, L, Stanley, CB & Harries, D 2016, 'Properties of Polyvinylpyrrolidone in a Deep Eutectic Solvent', Journal of Physical Chemistry A, vol. 120, no. 19, pp. 3253-3259. https://doi.org/10.1021/acs.jpca.5b11927
Sapir, L & Harries, D 2016, 'Macromolecular compaction by mixed solutions: Bridging versus depletion attraction', Current Opinion in Colloid and Interface Science, vol. 22, pp. 80-87. https://doi.org/10.1016/j.cocis.2016.02.010
Meirzadeh, E, Sapir, L, Cohen, H, Cohen, SR, Ehre, D, Harries, D, Lahav, M & Lubomirsky, I 2016, 'Nonclassical Crystal Growth as Explanation for the Riddle of Polarity in Centrosymmetric Glycine Crystals', Journal of the American Chemical Society, vol. 138, no. 44, pp. 14756-14763. https://doi.org/10.1021/jacs.6b09190
2015
Sapir, L & Harries, D 2015, 'Is the depletion force entropic? Molecular crowding beyond steric interactions', Current Opinion in Colloid and Interface Science, vol. 20, no. 1, pp. 3-10. https://doi.org/10.1016/j.cocis.2014.12.003
Sukenik, S, Sapir, L & Harries, D 2015, 'Osmolyte Induced Changes in Peptide Conformational Ensemble Correlate with Slower Amyloid Aggregation: A Coarse-Grained Simulation Study', Journal of Chemical Theory and Computation, vol. 11, no. 12, pp. 5918-5928. https://doi.org/10.1021/acs.jctc.5b00657
Sapir, L & Harries, D 2015, 'Macromolecular Stabilization by Excluded Cosolutes: Mean Field Theory of Crowded Solutions', Journal of Chemical Theory and Computation, vol. 11, no. 7, pp. 3478-3490. https://doi.org/10.1021/acs.jctc.5b00258
2014
Sapir, L & Harries, D 2014, 'Origin of enthalpic depletion forces', Journal of Physical Chemistry Letters, vol. 5, no. 7, pp. 1061-1065. https://doi.org/10.1021/jz5002715
2013
Sukenik, S, Sapir, L, Gilman-Politi, R & Harries, D 2013, 'Diversity in the mechanisms of cosolute action on biomolecular processes', Faraday Discussions, vol. 160, pp. 225-237. https://doi.org/10.1039/c2fd20101a
Sukenik, S, Sapir, L & Harries, D 2013, 'Balance of enthalpy and entropy in depletion forces', Current Opinion in Colloid and Interface Science, vol. 18, no. 6, pp. 495-501. https://doi.org/10.1016/j.cocis.2013.10.002
2011
Sapir, L & Harries, D 2011, 'Linking trehalose self-association with binary aqueous solution equation of state', Journal of Physical Chemistry B, vol. 115, no. 4, pp. 624-634. https://doi.org/10.1021/jp109780n
2009
Politi, R, Sapir, L & Harries, D 2009, 'The impact of polyols on water structure in solution: A computational study', Journal of Physical Chemistry A, vol. 113, no. 26, pp. 7548-7555. https://doi.org/10.1021/jp9010026