Publications
Neural correlates of subjective cognitive decline in adults at high risk for Alzheimer's disease
Ben-Ami L, Ravona-Springer R, Tsarfaty G, Raizman R, Shumacher A, Sharvit-Ginon I, Greenbaum L, B Bendlin B, Okun E, Heymann A, Schnaider Beeri M, Livny A. , 2023
Early diagnosis and treatment of Alzheimer’s disease by targeting toxic soluble Aβ oligomers.
Habashi M, Vutla S, Tripathi K, Senapati S, Chauhan PS, Haviv-Chesner A, Richman M, Mohand SA, Dumulon-Perreault V, Mulamreddy R, Okun E, Chill JH, Guérin B, Lubell WD, Rahimipour S. , 2022
Physiology and pharmacology of amyloid precursor protein
Cho Y, Bae HG, Okun E, Arumugam TV, Jo DG, 2022
COVID-19 Vaccination of Individuals with Down Syndrome-Data from the Trisomy 21 Research Society Survey on Safety, Efficacy, and Factors Associated with the Decision to Be Vaccinated
Hüls A, Feany PT, Zisman SI, Costa ACS, Dierssen M, Balogh R, Bargagna S, Baumer NT, Brandão AC, Carfi A, Chicoine BA, Ghosh S, Lakhanpaul M, Levin J, Lunsky Y, Manso C, Okun E ,Real de Asua D, Rebillat AS, Rohrer TR, Sgandura G, Valentini D, Sherman SL, , 2022
HCAR1‑Mediated l‑Lactate Signaling Suppresses Microglial Phagocytosis
Nicola R, Madar R and Okun E, 2022
Integrative epigenomic and transcriptomic analyses reveal metabolic switching by intermittent fasting in brain
2022
Sleeve Gastrectomy Reduces Glycemia but Does Not Affect Cognitive Impairment in Lean 5xFAD Mice.
Samuel I, Ben Haroush, Schyr R, Arad Y, Attali T, Azulai S, Bergel M, Halfon A, Hefetz L, Hirsch T, Israeli H, Lax N, Nitzan K, Sender D, Sweetat S, Okun E, Rosenmann H and Ben-Zvi D. , 2022
Induction of an effective anti-Amyloid-beta humoral response in aged mice
Illouz T, Madar R , Hirsh T , Biragyn A and Okun E, 2021
Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome
Illouz T, Biragyn A, Florencia Iulita M, Flores-Aguilar L, Dierssen M, De Toma I, Antonarakis S.E, Yu E, Herault Y, Potier M.C, Botté A, Roper R, Sredni B, London J, Mobley W, Strydom A and Okun E. , 2021
Therapeutic B-cell depletion reverses progression of Alzheimer's disease
Kim K, Wang X, Ragonnaud E, Bodogai M, Illouz T, DeLuca M, McDevitt R.A, Gusev F, Okun E, Rogaev E and Biragyn A, 2021
Specific Susceptibility to COVID-19 in Adults with Down Syndrome
Illouz T, Biragyn A, Frenkel-Morgenstern M, Weissberg O, Gorohovski A, Merzon E, Green I, Iulita F, Flores-Aguilar L, Dierssen Sotos M, De Toma H, Lifshitz H, Antonarakis S.E, Yu E, Herault Y, Potier M.C, Botté A, Roper R, Sredni B, Sarid R, London J, M, 2021
High‑Intensity Functional Training: Molecular Mechanisms and Benefits
B. Zeev T and Okun E, 2021
Maternal antibodies facilitate Amyloid-β clearance by activating Fc-receptor-Syk-mediated phagocytosis
Illouz T, Nicola R, Ben-Shuhan L, Madar R, Biragyn R and Okun E, 2021
Mild physical activity does not improve spatial learning in a virtual environment
Okun E, B. Zeev T, Weiss I, Ashri S, Heled Y, Ketko I and Yanovich R, 2020
The effects of High-Intensity Functional Training (HIFT) on spatial learning, visual pattern separation and attention span in adolescents
Okun E, Ben-Zeev T, Hirsh T, Weiss I and Gornstein M, 2020
A modified Barnes maze for an accurate assessment of spatial learning in mice
Illouz T, Madar R and Okun E, 2020
L-Lactate Promotes Adult Hippocampal Neurogenesis
Lev-Vachnish Y, Cadury S, Rotter-Maskowitz A, Feldman N, Roichman A, Illouz T, Varvak A, Nicola R, Madar R and Okun E, 2019
Extracellular DAMPs in Plants and Mammals: Immunity, Tissue Damage and Repair
De Lorenzo G, Ferrari S, Cervone F and Okun E. , 2018
The Toll Pathway in the Central Nervous System of Flies and Mammals.
Shmueli A, Shalit T, Okun E and Shohat-Ophir G. , 2018
Dopamine receptors in the rat entopeduncular nucleus
Lavian H, Loewenstern Y, Madar R, Almog M, Bar-Gad I, Okun E and Korngreen A, 2018
Deficiency of Toll-like receptors 2, 3 or 4 extendslife expectancy inHuntington’s disease mice
Griffioen K, Mattson MP, Okun E, 2018
Restoring microglial and astroglial homeostasis using DNA immunization in a Down Syndrome mouse model
Illouz T., Madar R., Biragyn A. and Okun E, 2018
The effect of nanoparticle size on the ability to cross the blood–brain barrier: an in vivo study
Betzer O, Shilo M, Opochinsky R, Barnoy E, Motiei M, Okun E, Yadid G and Popovtzer R, 2017
Toll-like receptor 3 deficiency decreases epileptogenesis in pilocarpine model of SE-induced epilepsy in mice
Gross A, Benninger F ,Madar R, Illouz T, Griffioen K, Steiner I, Offen D and Okun E, 2017
Sirt6 alters adult hippocampal neurogenesis
Okun E, Marton D, Cohen D, Griffioen K, Kanfi Y, Illouz T, Madar R, Cohen HY, 2017
Dopaminergic modulation of synaptic integration and firing patterns in the rat entopenduncular nucleus
Lavian H, Almog M, Madar R, Loewenstern Y, Bar-Gad I, Okun E, Korngreen A, 2017
A protocol for quantitative analysis of murine and human amyloid-β1-40 and 1-42.
Illouz T , Madar R, Griffioen K and Okun E, 2017
Unbiased classification of spatial strategies in the Barnes maze
Illouz T , Madar R, Clague C , Griffioen K, Louzoun Y and Okun E, 2016
Unraveling cognitive traits using the Morris water maze unbiased strategy classification (MUST-C) algorithm
Illouz T, Madar R, Louzon Y, Griffioen KJ, Okun E, 2015
Postnatal TLR2 activation impairs learning and memory in adulthood
Madar R, Rotter A, Ben-Asher HW, Mughal MR, Arumugam TV, Wood WH 3rd, Becker KG, Mattson MP, Okun E, 2015
DAMPs as mediators of sterile inflammation in aging-related pathologies
Feldman N, Rotter A, Okun E, 2015
No ECSIT-stential evidence for a link with Alzheimer's disease yet.
Illouz T and Okun E., 2014
Cardiovascular Fitness and Cognitive Spatial Learning in Rodents and in Humans.
Barak B, Feldman N and Okun E, 2014
Toll-like receptors as developmental tools that regulate neurogenesis during development: an update.
Barak B, Feldman N and Okun E, 2014