Karasik Lab

Accessibility Accessibility

Welcome to The Musculoskeletal Genetics Lab

Karasik Lab

The primary objective of our research is to understand the biology reflected in the complex pathology of musculoskeletal aging and disease. Our research focuses on identifying genes underlying the heritable variation of human complex traits, such as susceptibility to osteoporotic fractures, muscle wasting, and metabolic syndrome.  Zebrafish (Danio rerio) serves as a valuable model for the cross-talk between these organs and tissues.

Learn more

Fields of Interest

About our research

Learn more

Human Musculoskeleton

Learn more

Multi-ancestry whole genome sequencing analysis of lean body masshole genome sequencing analysis of lean body mass

Learn more

Recent Publications

Rivas, Daniel ; Baltasar-Fernandez, Ivan ; AlOkda, Abdelrahman et al. / Picolinic acid, a tryptophan metabolite, exhibits anabolic effects in muscle cells and improves lifespan and movement in C. elegans. In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2026 ; Vol. 81, No. 1.
For more information
Zhang, Xiaoyu ; Su, Kuan Jui ; Banerjee, Bodhisattwa et al. / Multi-ancestry whole genome sequencing analysis of lean body mass. In: Genome Biology. 2025 ; Vol. 26, No. 1.
For more information
Mesika, Aviv ; Nadav, Golan ; Ben-David, Sapir et al. / Impaired Proteostasis is Linked to Neurological Pathology in a Zebrafish NGLY1 Deficiency Model. In: Journal of Inherited Metabolic Disease. 2025 ; Vol. 48, No. 4.
For more information
Malavašič, Petra ; Lojk, Jasna ; Lovšin, Marija Nika et al. / Membrane Palmitoylated Protein 7 is Required for Osteogenesis and is Linked with Bone Mineralization and Osteoporosis : The Functional Evaluation of GEFOS GWAS Hit. In: Calcified Tissue International. 2025 ; Vol. 116, No. 1.
For more information
All Publications

Contact Us

Site Editor Login